Postdoc Human Genetics at Leiden University Medical Center
Urenomvang dienstverband: fulltime
Aantal uur: 36 hours per week
Soort dienstverband: duration project
Lengte dienstverband: min. 1 year
Salaris: max. € 4,615
A postdoc position is open for an exciting research project at the LUMC in collaboration with a pharmaceutical company aiming to develop antibodies-based therapy to adult muscle degeneration. If you want to help find a new product that could help patients, this is the right job for you!
· You have a recent PhD degree Molecular Biology, Genetics or related studies
· Experience in cloning (expression systems), RNA and protein procedures is required.
· You have extensive experience with cell biology and in high-throughput imaging-based screens
· You have experience in mouse physiology and histology, and are in possession of ‘Article 12/13f’ that allows you to work with mouse models
· You are communicative, well organized, independent and willing to supervise
What you do
The project is a research collaboration between the lab of Vered Raz and a pharmaceutical company. As a postdoc you will screen molecules as candidate drugs to reduced muscle function in vitro (cell models) and in mouse models. You will need to develop the project so a creative mind is a pre. Communication will predominantly be in English
The Department of Human Genetics is a broadly oriented research department, led by Professor Silvère van der Maarel, with a focus on the (epi)genomic contribution to monogenic, multifactorial and acquired diseases, and the translation into clinical relevance. The department consists of 23 research units, embedded in four overarching research themes. You will work in the group of Dr. Vered Raz, who investigates molecular mechanisms in age-associated muscle degeneration and adult muscular disorders, with the end-point to develop specific therapeutics and biomarkers for those conditions.
We are looking for a candidate who has extensive experience with cell biology and molecular biology. Experience in high-throughput imaging screens is also important. Since you will be working with mouse models, an article 12/13f qualification and experience in mouse physiology and histology are necessary. You should be highly motivated, creative and willing to supervise. Within this project most communication will be in English, so fluency in English and excellent communication and organisational skills are essential.
Your career at the LUMC
The LUMC stimulates you in maintaining and developing your knowledge and skills. We offer internal courses and continuous training as well as services in terms of mobility, personal development and career advice.
You will be appointed for one year, with a possible extension for an additional year.
For this position, a letter of motivation describing your interest in the research area, a curriculum vitae, and the contact details of at least two references are requested. The application procedure will include one or more interviews and you will be asked to give a presentation.