LED3 -The Discovery and Mechanism of Lipid Transport Inhibition by the Antibiotic Zosurabalpin

The LED3 community is pleased to announce that Dr. Thomas Clairfeuille from the Roche Innovation Center in Basel will give the next LED3 Lecture on March 26th, 2026, at 16:00 in the Gorlaeus Collegezalengebouw, room C1.

There will be drinks after the lecture.

Thomas is one of the scientists who were key to driving forward the development of a new antibiotic class, that targets the LPS transport in Gram-negative bacteria. It also has the potential to open a completely novel mechanism-of-action for antibiotics against the most devastating bacterial infections.

He will talk about the discovery, the structural biology, the mechanism-of action and the development of the antibiotic Zosurabalpin that is now moving to phase 3 clinical studies against infections with carbapenem-resistant A. baumannii (CRAB).

Free walk in, no need for registration!

LED3 Lectures

The LED3 hub, consisting of researchers from the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden (IBL), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institute of Advanced Computer Science (LIACS), are very excited to organize the “LED3 Lectures”.

This lecture series brings world-leading researchers in the field of early drug discovery to our university and exposes our students to the many different aspects of top science conducted in this area.

Furthermore, it strengthens the network and the active exchange of researchers across our three member institutes and, in this way, fosters interdisciplinary research at Leiden University and beyond.

Looking forward to seeing you there!