OrganoPlate UF enables physiologically relevant tissue models by using unidirectional, gravity-driven flow, removing the need for external pumps. This approach simplifies operation while maintaining biological accuracy. With support for up to 512 chips in a single setup, researchers can conduct large-scale studies efficiently.
Features of OrganoPlate UF
• Unidirectional flow: Better replicates blood circulation, making it suitable for cardiovascular, oncology, and immunology research.
• Pump-free, gravity-driven design: Reduces complexity while maintaining conditions similar to the human body.
• Compatible with standard lab equipment: Works with existing liquid handling and imaging systems for efficient, high-throughput analysis.
• Supports long-term studies: Designed for extended culture of complex tissues, including those for chronic disease research.
Expanding Research Possibilities
“For over a decade, the MIMETAS OrganoPlate has been used worldwide to study human disease,” said Bas Trietsch, MIMETAS co-founder. “With UniFlow, we now offer unidirectional flow that closely mimics natural circulation while keeping our system easy to use.”
OrganoPlate UF is already integrated into MIMETAS’ liver, lung, brain, vasculature, and tumor models, supporting research in metabolic, cardiovascular, immunological, and cancer studies. The platform is now available as part of MIMETAS’ research services.
About MIMETAS
MIMETAS (Leiden, Netherlands) develops human-relevant disease models for drug discovery and development. The OrganoPlate® platform powers research for leading pharmaceutical companies worldwide. Founded in 2013, MIMETAS operates in Europe, Asia, and the USA. The company is based at Leiden Bio Science Park, a leading hub for life sciences innovation in the Netherlands.
The Court of Audit visited LBSP to explore how science and entrepreneurship create public value, with stops at TNO, Peregrion, NTrans, and VarmX sparking discussion on biotech innovation.
Leiden University is studying emotions at Lowlands Festival through two projects: a haunted house that measures how people cope with fear, and a silent performance exploring nonverbal communication.
LUMC and Stichting DON have launched Cure One, a new research center focused on accelerating curative therapies for type 1 diabetes through stem cell technology and immune-based treatments.